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The conjugation of GSH with xenobiotics including anticancer drugs can, indeed, lead to a double effect: on the one hand, xenobiotics might lose their damaging effect [90]
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Epimedii Herba), was found to attenuate the progression of CKD and the loss of structural and functional integrity of kidney tissue, as evidenced by reduced serum levels of uric acid, creatinine, and blood urea nitrogen (Figure 1) The active ingredient of Ginseng, ginsenoside-Rd, has been found to protect against renal failure induced by cisplatin administration through a reduction in oxidative stress and an inhibition of DNA fragmentation (Yokozawa and Dong, 2001)